Conjugated linoleic acids (CLA) are a family of over 28 isomers of linoleic acid found abundantly in the meat and dairy products.
Conjugated linoleic acid has been shown to reduce body fat accumulation in several animal models and CLA reduces body fat accumulation whether animals are fed a high-fat or low-fat diet, as the mechanism involved in reducing body fat by increased energy expenditure, which is observed within one week of CLA feeding and is sustained for at least six weeks. The increased energy expenditure is sufficient to account for the decreased fat accumulation(1)
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(1) "Changes in body composition with conjugated linoleic acid" by DeLany JP, West DB.