In the searching an optimal diet for improving glucose and lipid profiles in obese patients with type 2 diabetes, 35 free-living obese patients with type 2 diabetes were assigned to one of three 1,600 kcal/day diets for 12 weeks. The diets were high carbohydrate (10% fat, 4% saturated), high monounsaturated fat (MUFA) (32% fat, 7% saturated), or high saturated fat (SFA) (32% fat, 17% saturated), conducted by University of Adelaide (1) Scientists found that energy restriction, independent of diet composition, improves glycemic control; however, reducing SFA intake by replacing SFA with carbohydrate or MUFA reduces LDL maximally during weight loss and to a greater degree than has been shown in weight-stable studies.
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(1) "Effect of energy restriction, weight loss, and diet composition on plasma lipids and glucose in patients with type 2 diabetes" by Heilbronn LK, Noakes M, Clifton PM., posted in PubMed
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