Friday, March 9, 2012

Very-low-carbohydrate diet vs High-carbohydrate diet In Renal Function

Low-carbohydrate diets or low-carb diets are defined as a dietary programs that reduce the consumption of carbohydrate for weight control or for the treatment of obesity.
High-carbohydrate diet is the maximun intake of carbohydrate dietary programs. Some experts indicated that the program also promotes weight loss and reduce the risk of obesity(a)
There is always a concern that very-low-carbohydrate diets is the potential for increased risk of renal disease associated with a higher protein intake. In the assessment of renal function in 68 men and women with abdominal obesity (age 51.5+/-7.7 years, body mass index [calculated as kg/m(2)] 33.6+/-4.0) without preexisting renal dysfunction who were randomized to consume either an energy-restricted ( approximately 1,433 to 1,672 kcal/day), planned isocaloric very-low-carbohydrate (4% total energy as carbohydrate [14 g], 35% protein [124 g], 61% fat [99 g]), or high-carbohydrate diet (46% total energy as carbohydrate [162 g], 24% protein [85 g], 30% fat [49 g]) for 1 year. Body weight, serum creatinine, estimated glomerular filtration rate and urinary albumin excretion were assessed before and after 1 year , conducted by Commonwealth Scientific and Industrial Research Organisation(1), showed that long-term weight loss with a very-low-carbohydrate diet does not adversely affect renal function compared with a high-carbohydrate diet in obese individuals with normal renal function.

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